Description

5-Bromo-2-Fluoro-6-Ethoxyphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those containing complex halogenated biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific halogenated aromatic frameworks.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organoboron reagents.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A vital component for custom synthesis houses serving the life sciences sector with tailored chemical entities.

Basic Information

Product Name	5-Bromo-2-Fluoro-6-Ethoxyphenylboronic Acid
CAS No.	1315340-54-5
Molecular Formula	C8H9BBrFO3
Molecular Weight	262.87 g/mol
Synonyms	(5-Bromo-2-fluoro-6-ethoxyphenyl)boronic acid; 2-Fluoro-5-bromo-6-ethoxybenzeneboronic acid; 5-Bromo-2-fluoro-6-ethoxybenzeneboronic acid; Boronic acid, B-(5-bromo-2-fluoro-6-ethoxyphenyl)-; 1315340-54-5; 5-Br-2-F-6-EtO-PhB(OH)2
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Fluoro-6-Ethoxyphenylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions. A Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (by 1H NMR and IR), and impurity profile is available for each lot upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.