Description

2-Bromo-3-Fluoro-6-Methylphenylboronicacid is a specialized organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Building block for the development of organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers.
• Cross-Coupling Reactions: Essential reagent in palladium-catalyzed Suzuki-Miyaura reactions for carbon-carbon bond formation.
• Chemical Library Development: Employed in high-throughput screening and combinatorial chemistry to generate diverse compound libraries for biological testing.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands and catalysts used in asymmetric synthesis.

Basic Information

Product Name	2-Bromo-3-Fluoro-6-Methylphenylboronicacid
CAS No.	1315340-53-4
Molecular Formula	C7H7BBrFO2
Molecular Weight	232.85 g/mol
Synonyms	(2-Bromo-3-fluoro-6-methylphenyl)boronic acid; 2-Bromo-3-fluoro-6-methylbenzeneboronic acid; B-(2-Bromo-3-fluoro-6-methylphenyl)boronic acid; 2-Bromo-3-fluoro-p-tolylboronic acid; 1315340-53-4; Boronic acid, B-(2-bromo-3-fluoro-6-methylphenyl)-; AKOS026710194
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Fluoro-6-Methylphenylboronicacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, confirming compliance with customer requirements and industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (argon or nitrogen) to prevent degradation. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.