Description

2-Bromo-4,6-Difluorophenylboronic Acid is a high-purity, multi-functional organoboron building block essential for modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries to synthesize novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogen and fluorine substituents for bioactivity.
• Material Science Research: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials through palladium-catalyzed coupling.
• Chemical Biology & Probe Development: Employed in the construction of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Cross-Coupling Reactions: Primarily utilized in Suzuki-Miyaura cross-coupling to introduce the 2-bromo-4,6-difluorophenyl moiety into more complex aromatic and heteroaromatic systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations that require reliable, high-quality building blocks for client-directed synthetic projects.

Basic Information

Product Name	2-Bromo-4,6-Difluorophenylboronic Acid
CAS No.	1315339-48-0
Molecular Formula	C6H4BBrF2O2
Molecular Weight	236.81 g/mol
Synonyms	(2-Bromo-4,6-difluorophenyl)boronic Acid; B-(2-Bromo-4,6-difluorophenyl)boronic Acid; 2-Bromo-4,6-difluorobenzeneboronic Acid; 4,6-Difluoro-2-bromophenylboronic Acid; Boronic acid, B-(2-bromo-4,6-difluorophenyl)-; 1315339-48-0; AKOS015915024
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4,6-Difluorophenylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.