Description

6-Amino-3-Chloropyridine-2-Carbonitrile is a high-value, multi-functional heterocyclic building block. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced crop protection agents, and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and coordination complexes.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological systems and pathways.
• Cross-Coupling Reactions: The chloro and amino groups provide orthogonal handles for palladium-catalyzed cross-coupling and other metal-mediated transformations.
• Heterocyclic Library Synthesis: A versatile starting material for generating diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	6-Amino-3-Chloropyridine-2-Carbonitrile
CAS No.	1314976-40-3
Molecular Formula	C6H4ClN3
Molecular Weight	153.57 g/mol
Synonyms	3-Chloro-6-aminopyridine-2-carbonitrile; 2-Cyano-3-chloro-6-aminopyridine; 2-Pyridinecarbonitrile, 6-amino-3-chloro-; 6-Amino-3-chloro-2-cyanopyridine; 3-Chloro-2-cyano-6-aminopyridine; 6-Amino-3-chloropicolinonitrile; 1314976-40-3
EINECS	Contact for details

Quality Control

Our 6-Amino-3-Chloropyridine-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.