Description

cis-3-Fluorocyclobutanol is a versatile fluorinated cyclobutane derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring a fluorine atom and a hydroxyl group on the cyclobutane ring, enables precise molecular modifications essential for developing novel compounds. This high-purity intermediate is primarily sought after by pharmaceutical and agrochemical R&D teams for applications in medicinal chemistry and the creation of new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, pesticides, and fungicides with enhanced properties.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced materials with specific thermal or chemical resistance.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research exploring the effects of fluorine substitution on molecular conformation and reactivity.
• Fine Chemical Production: Acts as a building block for the manufacture of complex, high-value specialty chemicals.

Basic Information

Product Name	cis-3-Fluorocyclobutanol
CAS No.	1314961-80-2
Molecular Formula	C4H7FO
Molecular Weight	90.10 g/mol
Synonyms	(1r,3s)-3-Fluorocyclobutanol; (1R,3S)-3-Fluorocyclobutan-1-ol; 3-Fluorocyclobutanol (cis-); cis-3-Fluorocyclobutan-1-ol; Fluorocyclobutanol; 3-Fluoro-cis-cyclobutanol
EINECS	Contact for details

Quality Control

Our cis-3-Fluorocyclobutanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and production. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.