Description

2-(Difluoromethyl)Cyclopropanecarboxylic Acid is a high-value, fluorinated cyclopropane building block essential for advanced organic synthesis. This compound is prized for its unique structural motif, which combines the conformational rigidity of the cyclopropane ring with the electronic and steric properties of a difluoromethyl group. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, enabling the development of novel active ingredients with enhanced properties. Its precise synthesis and reliable supply are paramount for innovation in life sciences.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery and development, particularly for candidates targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the difluoromethyl group can improve bioavailability and environmental stability.
• Material Science Precursor: Employed in the synthesis of specialty polymers and liquid crystals, where fluorinated cyclopropanes can impart unique thermal and optical properties.
• Medicinal Chemistry Research: Facilitates structure-activity relationship (SAR) studies and the exploration of novel chemical space in lead optimization programs.
• Fluorine Chemistry Building Block: A versatile reagent for introducing the valuable difluoromethylcyclopropyl moiety into target molecules, a challenging transformation.

Basic Information

Product Name	2-(Difluoromethyl)Cyclopropanecarboxylic Acid
CAS No.	1314960-20-7
Molecular Formula	C5H6F2O2
Molecular Weight	136.10 g/mol
Synonyms	2-(Difluoromethyl)cyclopropane-1-carboxylic acid; 1-Cyclopropanecarboxylic acid, 2-(difluoromethyl)-; Difluoromethylcyclopropanecarboxylic Acid; (2-(Difluoromethyl)cyclopropyl)formic acid; 1314960-20-7; 2-Difluoromethylcyclopropanecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-(Difluoromethyl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for research and commercial synthesis. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.