Description

1-Chloro-3-Fluoro-5-(Methylsulfanyl)Benzene is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. This compound is valued for its unique combination of halogen and sulfur-containing functional groups, which enable precise molecular modifications in complex organic frameworks. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Used in the synthesis of functionalized monomers for specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An effective substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive chlorine and fluorine substituents.
• Ligand and Catalyst Development: Employed in the preparation of novel sulfur-containing ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	1-Chloro-3-Fluoro-5-(Methylsulfanyl)Benzene
CAS No.	1314939-89-3
Molecular Formula	C7H6ClFS
Molecular Weight	176.64 g/mol
Synonyms	3-Chloro-5-Fluoro(methylthio)benzene; 5-Chloro-1-Fluoro-3-(Methylsulfanyl)Benzene; 1-Chloro-3-Fluoro-5-(Methylthio)Benzene; 3-Chloro-5-fluorophenyl methyl sulfide; Benzene, 1-chloro-3-fluoro-5-(methylthio)-; 5-Chloro-3-fluoro phenyl methyl sulfide; (3-Chloro-5-fluorophenyl)(methyl)sulfane
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-Fluoro-5-(Methylsulfanyl)Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates and ISO standards for industrial chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.