Description

2-Acetoxy-4,4,4-Trifluorobutyronitrile is a high-value fluorinated organic intermediate characterized by its acetoxy and nitrile functional groups. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of a trifluoromethyl group can dramatically alter biological activity and metabolic stability. It is primarily sought after by research chemists and process development scientists in fine chemical and advanced material manufacturing.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a trifluoromethylated backbone to enhance potency and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where fluorine substitution improves efficacy and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated components in electronic display technologies and organic light-emitting diodes.
• Fluorinated Polymer Modification: Employed to introduce functional side chains into polymers, altering their surface properties, chemical resistance, and performance characteristics.
• Organic Synthesis Reagent: Utilized in advanced organic reactions, including nucleophilic substitutions and cyclizations, to construct complex heterocyclic frameworks.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new chemical spaces and developing novel fluorination methodologies.

Basic Information

Product Name	2-Acetoxy-4,4,4-Trifluorobutyronitrile
CAS No.	1314914-15-2
Molecular Formula	C6H6F3NO2
Molecular Weight	181.11 g/mol
Synonyms	4,4,4-Trifluoro-2-hydroxybutyronitrile acetate; 2-(Acetyloxy)-4,4,4-trifluorobutanenitrile; 4,4,4-Trifluoro-2-acetoxybutyronitrile; 2-Acetoxy-4,4,4-trifluorobutyronitrile; Butyronitrile, 2-(acetyloxy)-4,4,4-trifluoro-; Acetic acid 2-cyano-4,4,4-trifluorobutyl ester
EINECS	Contact for details

Quality Control

Our 2-Acetoxy-4,4,4-Trifluorobutyronitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request. We adhere to cGMP principles for pharmaceutical-grade material upon demand.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage or when working with large quantities to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.