Description

3-Benzyloxy-±-Aminopropionitrile is a versatile chiral nitrile building block of significant interest in advanced organic synthesis. Its primary value lies in its bifunctional structure, featuring both a protected amino group and a reactive nitrile moiety, enabling its use in the construction of complex nitrogen-containing molecules. This intermediate is particularly valuable for pharmaceutical research and development, serving as a key precursor for active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in the development of enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, including complex amines, amino acids, and heterocyclic compounds.
• Asymmetric Synthesis: Employed in chiral pool synthesis and as a starting material for catalysts or ligands used in stereoselective transformations.
• Peptidomimetic Research: Useful in the design and synthesis of peptide analogs and conformationally restricted scaffolds for medicinal chemistry.

Basic Information

Product Name	3-Benzyloxy-±-Aminopropionitrile
CAS No.	1314897-97-6
Molecular Formula	C10H12N2O
Molecular Weight	176.22 g/mol
Synonyms	3-(Benzyloxy)aminopropanenitrile; (±)-3-(Benzyloxyamino)propionitrile; 3-(Benzyloxyamino)propanenitrile; 3-Benzyloxyaminopropionitrile; 3-(N-Benzyloxyamino)propionitrile; Aminopropionitrile, 3-benzyloxy-; Benzyloxyaminopropionitrile; O-Benzylhydroxylamine propionitrile adduct
EINECS	Contact for details

Quality Control

Our 3-Benzyloxy-±-Aminopropionitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Racemic mixture (±)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.