Description

1-(4-Cyanophenyl)Cyclobutanecarboxylic Acid is a high-purity, synthetically versatile organic building block featuring a cyclobutane ring and a cyano-substituted aromatic system. This compound is valued for its unique structural rigidity and functional handles, making it a critical intermediate in advanced organic synthesis. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for constructing novel active molecules, particularly in medicinal chemistry programs targeting new therapeutic entities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for constructing complex molecular scaffolds with potential biological activity.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where the cyclobutane core can impart favorable metabolic stability and potency.
• Material Science Research: Serves as a precursor for specialty polymers or liquid crystals, leveraging its aromatic and carboxylic acid functionalities.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for cycloaddition reactions, ring-opening transformations, and as a precursor to other functionalized cyclobutane derivatives.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1-(4-Cyanophenyl)Cyclobutanecarboxylic Acid
CAS No.	1314710-36-5
Molecular Formula	C12H11NO2
Molecular Weight	201.22 g/mol
Synonyms	4-(1-Carboxycyclobutyl)benzonitrile; 1-(4-Cyanophenyl)cyclobutanecarboxylic acid; Cyclobutanecarboxylic acid, 1-(4-cyanophenyl)-; p-Cyanophenylcyclobutanecarboxylic Acid; 4-(Cyclobutane-1-carbonyl)benzonitrile (precursor form); 1-(4-CN-Ph)-Cyclobutanecarboxylic Acid; Benzonitrile, 4-(1-carboxycyclobutyl)-
EINECS	Contact for details

Quality Control

Our 1-(4-Cyanophenyl)Cyclobutanecarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for that lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.