Description

tert-Butyl 4-(Azetidin-3-Yl)Piperidine-1-Carboxylate is a high-value, protected heterocyclic amine building block of significant importance in modern pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the areas of central nervous system (CNS) and metabolic disorder therapeutics. It is primarily utilized by medicinal chemists and process development scientists in pharmaceutical companies and contract research organizations (CROs) to construct complex molecular architectures. The CAS number for this compound is 1314703-47-3.

Application

This versatile chemical intermediate is designed for advanced synthetic applications, enabling the creation of sophisticated drug candidates.

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates targeting G-protein-coupled receptors (GPCRs) and kinases.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to improve potency and selectivity.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and route development for potential APIs.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery programs.
• Chemical Biology Probes: Useful for creating tool compounds to study biological pathways and target validation.

Basic Information

Product Name	tert-Butyl 4-(Azetidin-3-Yl)Piperidine-1-Carboxylate
CAS No.	1314703-47-3
Molecular Formula	C13H24N2O2
Molecular Weight	240.34 g/mol
Synonyms	1-Boc-4-(azetidin-3-yl)piperidine; 1-(tert-Butoxycarbonyl)-4-(azetidin-3-yl)piperidine; tert-Butyl 4-(3-azetidinyl)-1-piperidinecarboxylate; 4-(Azetidin-3-yl)piperidine-1-carboxylic acid tert-butyl ester; 3-(1-Boc-4-piperidyl)azetidine; 1-Piperidinecarboxylic acid, 4-(3-azetidinyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(Azetidin-3-Yl)Piperidine-1-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC/NMR), identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.