Description

2-(2-Cyanophenyl)-2-Methylpropanoic Acid is a specialized organic building block featuring a cyano-substituted phenyl ring and a tertiary carboxylic acid group. This unique structure makes it a valuable intermediate for synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by research chemists and process development scientists for constructing active pharmaceutical ingredients (APIs) and advanced materials. The compound, identified by CAS NO 1314655-77-0, is supplied in high purity to ensure reliable and reproducible reaction outcomes.

Application

This versatile chemical intermediate serves critical roles in advanced organic synthesis across several high-value industries.

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or acting as enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Advanced Material Research: Employed in the development of organic semiconductors, liquid crystals, and polymers with specific optical or electronic properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-(2-Cyanophenyl)-2-Methylpropanoic Acid
CAS No.	1314655-77-0
Molecular Formula	C11H11NO2
Molecular Weight	189.21 g/mol
Synonyms	2-(2-Cyanophenyl)-2-methylpropanoic acid; α-Cyano-o-toluic acid, α,α-dimethyl-; 2-Methyl-2-(2-cyanophenyl)propanoic acid; 2-Cyano-α,α-dimethylbenzenacetic acid; o-Cyanophenylisobutyric acid; (2-Cyanophenyl)isobutyric acid; 1314655-77-0; 2-(2-Cyanophenyl)-2-methylpropionic acid
EINECS	Contact for details

Quality Control

Our 2-(2-Cyanophenyl)-2-Methylpropanoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP and ISO guidelines ensures the material meets the stringent requirements for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.