Description

3-Amino-2,2-difluoropropan-1-ol hydrochloride is a high-purity, specialized fluorinated building block essential for advanced organic synthesis. This compound is valued for its unique difluoromethyl and amino alcohol functionalities, which are critical for modulating the physicochemical properties of target molecules. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated drug candidates, particularly in protease inhibitor and kinase inhibitor research.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides where the difluoromethyl group enhances metabolic stability and bioavailability.
• Fluorinated Amino Alcohol Precursor: Serves as a versatile chiral building block for asymmetric synthesis and the creation of fluorinated ligands or catalysts.
• Material Science Research: Employed in the synthesis of fluorinated polymers or specialty chemicals with unique surface properties.
• Peptidomimetics: Incorporated into peptide backbones to improve resistance to enzymatic degradation and alter conformational properties.

Basic Information

Product Name	3-Amino-2,2-difluoropropan-1-ol hydrochloride
CAS No.	1314395-95-3
Molecular Formula	C₃H₈ClF₂NO
Molecular Weight	147.55 g/mol
Synonyms	2,2-Difluoro-3-aminopropan-1-ol hydrochloride; 3-Amino-2,2-difluoropropyl alcohol hydrochloride; 1-Propanol, 3-amino-2,2-difluoro-, hydrochloride; 3-Amino-2,2-difluoro-1-propanol hydrochloride; 1314395-95-3; 3-Amino-2,2-difluoropropan-1-Olhcl
EINECS	Contact for details

Quality Control

Our 3-Amino-2,2-difluoropropan-1-ol hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.