Description

(2S,5S)-1-(2-(1,3-Dioxolan-2-Yl)Phenyl)-2,5-Diethylphospholane, 97% is a high-purity, chiral phospholane ligand of significant importance in asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, which is critical for producing single-enantiomer intermediates. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and fine chemical industries who require reliable, high-performance ligands for hydrogenation and other key synthetic transformations.

Application

• As a chiral ligand in asymmetric hydrogenation catalysts for pharmaceutical intermediate synthesis.
• Utilized in the development of novel catalytic systems for the production of enantiomerically pure agrochemicals.
• Employed in academic and industrial research for studying structure-activity relationships in phosphine ligand design.
• Critical component in the synthesis of specialty chemicals requiring high levels of stereochemical control.
• Used in process chemistry to optimize yield and enantiomeric excess (ee) in scale-up reactions.

Basic Information

Product Name	(2S,5S)-1-(2-(1,3-Dioxolan-2-Yl)Phenyl)-2,5-Diethylphospholane, 97%
CAS No.	1314246-02-0
Molecular Formula	C17H25O2P
Molecular Weight	292.35 g/mol
Synonyms	(2S,5S)-2,5-Diethyl-1-[2-(1,3-dioxolan-2-yl)phenyl]phospholane; (2S,5S)-1-(2-(1,3-Dioxolan-2-yl)phenyl)-2,5-diethylphospholane; (S,S)-2,5-Diethyl-1-(2-(1,3-dioxolan-2-yl)phenyl)phospholane; DuanPhos; (S,S)-DuanPhos; (2S,5S)-DuanPhos; Chiral DuanPhos ligand; Asymmetric phospholane ligand
EINECS	Contact for details

Quality Control

Our (2S,5S)-1-(2-(1,3-Dioxolan-2-Yl)Phenyl)-2,5-Diethylphospholane, 97% is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral HPLC and NMR spectroscopy, to verify identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure long-term stability. Keep the container in a cool, dry, and well-ventilated area, separate from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.