Description

Boronic Acid, B-[2-[[3-(Trifluoromethyl)Phenyl]Methoxy]Phenyl]- is a specialized aromatic boronic acid derivative featuring a trifluoromethylphenyl ether moiety. This compound matters as a high-value synthetic intermediate, prized for its role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern pharmaceutical and agrochemical synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex biaryl and heterobiaryl scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl structures.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science: Serves as a monomer or cross-linking agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed as a molecular probe or in the development of boronic acid-based sensors and separation media.
• Catalyst Ligand Precursor: Can be utilized to synthesize novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	Boronic Acid, B-[2-[[3-(Trifluoromethyl)Phenyl]Methoxy]Phenyl]-
CAS No.	1313761-90-8
Molecular Formula	C14H12BF3O3
Molecular Weight	296.05 g/mol
Synonyms	[2-[[3-(Trifluoromethyl)phenoxy]phenyl]boronic acid; 2-([3-(Trifluoromethyl)phenoxy]phenyl)boronic acid; B-[2-[[3-(Trifluoromethyl)phenyl]methoxy]phenyl]boronic acid; (2-((3-(Trifluoromethyl)phenoxy)phenyl)boronic acid; 2-(3-Trifluoromethylphenoxy)benzeneboronic acid; Boronic acid, B-[2-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]- (9CI)
EINECS	Contact for details

Quality Control

Our Boronic Acid, B-[2-[[3-(Trifluoromethyl)Phenyl]Methoxy]Phenyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C or as specified on the label. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air and moisture must be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.