Description

3-Fluoro-4-((Methylamino)Methyl)Phenylboronic Acid CAS NO 1313738-12-3 is a specialized organoboron compound featuring both a boronic acid and a methylamino-methyl functional group on a fluorinated aromatic ring. This unique bifunctional structure makes it a highly valuable building block for modern synthetic chemistry, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical boronic acid partner for constructing biaryl and heterobiaryl structures, which are common motifs in medicinal chemistry.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and material science applications.
• Agrochemical Research: Employed in the development of new herbicides and pesticides with fluorinated aromatic components.
• Material Science: A building block for creating advanced organic electronic materials and polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems.

Basic Information

Product Name	3-Fluoro-4-((Methylamino)Methyl)Phenylboronic Acid
CAS No.	1313738-12-3
Molecular Formula	C8H11BFNO2
Molecular Weight	182.99 g/mol
Synonyms	(3-Fluoro-4-((methylamino)methyl)phenyl)boronic acid; B-[3-Fluoro-4-[(methylamino)methyl]phenyl]boronic acid; 3-Fluoro-4-(N-methylaminomethyl)benzeneboronic acid; 3-Fluoro-4-((methylamino)methyl)benzeneboronic acid; 4-Borono-2-fluoro-N-methylbenzylamine; 1313738-12-3; Boronic acid, B-[3-fluoro-4-[(methylamino)methyl]phenyl]-; AKOS025310647
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-((Methylamino)Methyl)Phenylboronic Acid is produced under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.