Description

(4-((2-Acrylamidoethyl)Carbamoyl)-3-Fluorophenyl)Boronic Acid is a specialized, high-value boronic acid derivative featuring an acrylamide functional group. This bifunctional structure is critical for its role as a versatile building block in advanced organic synthesis and materials science. It is primarily sought after by researchers and manufacturers in the pharmaceutical and polymer industries for developing targeted therapeutics and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of proteolysis-targeting chimeras (PROTACs) and other novel drug candidates, particularly those utilizing Suzuki-Miyaura cross-coupling reactions.
• Bioconjugation Reagent: Used for site-specific modification of proteins, peptides, and antibodies, leveraging the boronic acid group for binding and the acrylamide for covalent attachment.
• Polymer Chemistry: Serves as a functional monomer or cross-linker in the production of smart hydrogels, boronate-affinity materials, and stimuli-responsive polymers.
• Chemical Biology Probes: Enables the development of activity-based probes and sensors for detecting enzymes or specific analytes in biological systems.
• Material Science: Building block for creating advanced organic frameworks, surface coatings, and composite materials with tailored properties.
• Agrochemical Research: Intermediate in the research and development of new, more effective crop protection agents.

Basic Information

Product Name	(4-((2-Acrylamidoethyl)Carbamoyl)-3-Fluorophenyl)Boronic Acid
CAS No.	1313712-90-1
Molecular Formula	C₁₂H₁₄BFN₂O₃
Molecular Weight	264.06 g/mol
Synonyms	3-Fluoro-4-((2-(acrylamido)ethyl)carbamoyl)phenylboronic acid; 4-(2-Acrylamidoethylcarbamoyl)-3-fluorobenzeneboronic acid; N-(2-((4-Borono-2-fluorobenzoyl)amino)ethyl)acrylamide; Acrylamide-PEG2-Benzoic Acid-Boronic Acid (Fluoro); Boron, [4-[[[2-[(1-oxo-2-propen-1-yl)amino]ethyl]amino]carbonyl]-2-fluorophenyl]-; 1313712-90-1; AKOS006361950
EINECS	Contact for details

Quality Control

Every batch of (4-((2-Acrylamidoethyl)Carbamoyl)-3-Fluorophenyl)Boronic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95% (Typical: ≥97%)
Water Content (KF)	≤1.0%
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.