Description

2-Fluoro-5-(Methylsulfonyl)Phenylboronic Acid is a high-value, multi-functional boronic acid derivative essential for modern synthetic chemistry. Its core value lies in serving as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific fluorinated and sulfonyl-containing scaffolds.
• Material Science: Serves as a monomer or precursor for creating advanced organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Research: A vital reagent for CROs (Contract Research Organizations) and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Fluoro-5-(Methylsulfonyl)Phenylboronic Acid
CAS No.	1313617-71-8
Molecular Formula	C7H8BFO4S
Molecular Weight	217.01 g/mol
Synonyms	(2-Fluoro-5-(methylsulfonyl)phenyl)boronic acid; 2-Fluoro-5-methanesulfonylbenzeneboronic acid; 5-Methylsulfonyl-2-fluorophenylboronic acid; B-[2-Fluoro-5-(methylsulfonyl)phenyl]boronic acid; 2-Fluoro-5-(methylsulfonyl)benzeneboronic acid; 1313617-71-8; 2-Fluoro-5-methanesulphonylphenylboronic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(Methylsulfonyl)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. Certificates of Analysis (COA) with detailed chromatographic data are available for all shipments to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its boronic acid nature and sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation of reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.