Description

(S)-3-(4-Hydroxy-3-Methoxy-Phenyl)-3-Phenylacetylamino-Propionicacid is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters because it provides a critical, enantiomerically pure building block for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high stereochemical specificity. Pharmaceutical R&D and manufacturing organizations need this material for the synthesis of complex drug candidates, where its defined stereochemistry is essential for ensuring biological activity and meeting stringent regulatory requirements for chiral purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients, especially those targeting neurological or metabolic disorders.
• Asymmetric Synthesis: Serves as a precursor or reagent in asymmetric catalytic processes to construct molecules with defined stereocenters.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry Development: Used for scaling up synthetic routes from laboratory to pilot and commercial manufacturing scales.
• Reference Standard: Can be utilized as an analytical standard for method development and quality control of related compounds.

Basic Information

Product Name	(S)-3-(4-Hydroxy-3-Methoxy-Phenyl)-3-Phenylacetylamino-Propionicacid
CAS No.	1313278-17-9
Molecular Formula	C18H19NO5
Molecular Weight	329.35 g/mol
Synonyms	(S)-3-(4-Hydroxy-3-methoxyphenyl)-3-(2-phenylacetamido)propanoic acid; (S)-3-(4-Hydroxy-3-methoxyphenyl)-3-(phenylacetamido)propionic acid; (S)-HMPPA; (S)-3-Phenylacetylamino-3-(4-hydroxy-3-methoxyphenyl)propionic acid; (S)-Vanillyl-phenylalanine derivative; (S)-N-(3-(4-Hydroxy-3-methoxyphenyl)-3-carboxypropionyl)benzylamine; (S)-3-(4-Hydroxy-3-methoxybenzyl)-3-(phenylacetamido)propanoic acid
EINECS	Contact for details

Quality Control

Our production of (S)-3-(4-Hydroxy-3-Methoxy-Phenyl)-3-Phenylacetylamino-Propionicacid adheres to stringent quality management systems. The material undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure compliance with high-purity pharmaceutical intermediate standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.