Description

Z-D-Asn(Xan)-Oh is a protected amino acid derivative, specifically an N-xanthyl-protected D-asparagine building block, with the CAS registry number 1313054-82-8. This compound is a critical chiral synthon for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics, enabling precise control over stereochemistry and side-chain functionality. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, diagnostic agents, and biochemical probes.

Application

• Peptide Synthesis: A key protected intermediate for the controlled incorporation of D-asparagine into custom peptide sequences.
• Pharmaceutical Research: Used in the R&D of peptide-based drugs, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Bioconjugation: Serves as a building block for creating peptide tags, linkers, and modified biomolecules for diagnostic and labeling applications.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds.
• Academic Research: Utilized in university and institutional labs for studying peptide structure-activity relationships and synthetic methodology development.

Basic Information

Product Name	Z-D-Asn(Xan)-Oh
CAS No.	1313054-82-8
Molecular Formula	C19H18N2O6
Molecular Weight	370.36 g/mol
Synonyms	N(alpha)-Carbobenzoxy-N(beta)-(9H-xanthen-9-yl)-D-asparagine; Z-D-Asn(Xan)-OH; Z-D-Asparagine(Xan)-OH; N(alpha)-Z-N(beta)-Xan-D-asparagine; Cbz-D-Asn(Xan)-OH; Benzyloxycarbonyl-D-asparagine(N-xanthyl) acid; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-((9H-xanthen-9-yl)amino)-3-oxopropanoic acid; Fmoc-D-Asn(Xan)-OH (related Fmoc-protected variant)
EINECS	Contact for details

Quality Control

Every batch of Z-D-Asn(Xan)-Oh is manufactured and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, chiral purity, and identity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Chiral Purity (HPLC)	≥99.0% D-isomer
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.