Description

Fmoc-D-Harg-Oh CAS NO 1313054-69-1 is a high-purity, protected amino acid derivative specifically engineered for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise stereochemical control and side-chain protection in complex peptide sequences. It is an essential building block for the pharmaceutical and biotechnology industries, particularly in the development of novel therapeutic peptides, peptidomimetics, and research-grade biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the sequential assembly of peptides containing D-configured homoarginine residues.
• Pharmaceutical R&D: Used in the discovery and development of peptide-based drugs targeting metabolic disorders, cardiovascular diseases, and oncology.
• Bioconjugation: Serves as a functionalized linker or spacer molecule for creating peptide-protein or peptide-small molecule conjugates.
• Combinatorial Chemistry: A valuable component in libraries for high-throughput screening to identify new bioactive compounds.
• Proteomics Research: Employed in the synthesis of isotopically labeled peptides or peptide standards for mass spectrometry analysis.
• Antimicrobial Peptide (AMP) Development: Used to incorporate cationic arginine analogs to modulate the charge and activity of AMPs.

Basic Information

Product Name	Fmoc-D-Harg-Oh
CAS No.	1313054-69-1
Molecular Formula	C23H28N4O5
Molecular Weight	440.49 g/mol
Synonyms	Fmoc-D-homoarginine-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-homoarginine; Fmoc-D-HomoArg-OH; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-(diaminomethylideneamino)hexanoic acid; D-Fmoc-homoarginine; Fmoc-D-Harg; Fmoc-D-NG,NG'-bis-Boc-homoarginine (protected form precursor); D-Homoarginine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our Fmoc-D-Harg-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive pharmaceutical research. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.