Description

4-((4-Ethylpiperazin-1-Yl)Methyl)-3-Fluorophenylboronic Acid CAS NO 1312807-23-0 is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its molecular architecture, featuring both a boronic acid group and a substituted piperazine moiety, makes it an essential reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients. Its utility extends to advanced material science applications where precise molecular assembly is required.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine and boronic acid groups contribute to bioactivity and metabolic stability.
• Ligand Synthesis: Serves as a starting material for creating sophisticated ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target identification.
• Advanced Material Development: Utilized in the construction of organic frameworks and functional polymers with specific electronic or structural properties.
• Process Chemistry & Scale-up: Supports route scouting and optimization for the commercial-scale production of fine chemicals.

Basic Information

Product Name	4-((4-Ethylpiperazin-1-Yl)Methyl)-3-Fluorophenylboronic Acid
CAS No.	1312807-23-0
Molecular Formula	C13H20BFN2O2
Molecular Weight	266.12 g/mol
Synonyms	(3-Fluoro-4-((4-ethylpiperazin-1-yl)methyl)phenyl)boronic acid; 4-[(4-Ethyl-1-piperazinyl)methyl]-3-fluorobenzeneboronic acid; 3-Fluoro-4-((4-ethylpiperazin-1-yl)methyl)benzeneboronic acid; Boronic acid, B-[3-fluoro-4-[(4-ethyl-1-piperazinyl)methyl]phenyl]-; 1312807-23-0; 4-(4-Ethylpiperazin-1-ylmethyl)-3-fluorophenylboronic acid
EINECS	Contact for details

Quality Control

Our 4-((4-Ethylpiperazin-1-Yl)Methyl)-3-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.