Description

Dl-Cyclopropylglycine Ethyl Ester Hydrochloride is a protected amino acid derivative, specifically the ethyl ester hydrochloride salt of cyclopropylglycine. This compound is a crucial chiral building block in organic synthesis, valued for its ability to introduce the constrained cyclopropyl moiety into target molecules. It is primarily used by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, antiviral agents, and other bioactive molecules containing cyclopropyl amino acid motifs.
• Peptide Chemistry: Serves as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS).
• Agrochemical Research: Used in the development of novel herbicides and pesticides where the cyclopropyl group can enhance metabolic stability and binding affinity.
• Chemical Biology & Proteomics: Employed as a tool compound or labeled analog for studying enzyme mechanisms and protein interactions.
• Material Science: Potential monomer for creating specialized polymers with unique thermal and mechanical properties.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom synthesis of complex, high-value organic compounds for clients.

Basic Information

Product Name	Dl-Cyclopropylglycine Ethyl Ester Hydrochloride
CAS No.	1311313-77-5
Molecular Formula	C8H15NO2 · HCl
Molecular Weight	193.67 (Free base) / 230.12 (HCl salt)
Synonyms	DL-2-Amino-2-cyclopropylacetic acid ethyl ester hydrochloride; Ethyl 2-amino-2-cyclopropylacetate hydrochloride; Cyclopropylglycine ethyl ester HCl; (±)-2-Cyclopropylglycine ethyl ester hydrochloride; Amino(cyclopropyl)acetic acid ethyl ester hydrochloride; ACPG-OEt · HCl; Ethyl DL-α-amino-α-cyclopropylacetate hydrochloride
EINECS	Contact for details

Quality Control

Our Dl-Cyclopropylglycine Ethyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and IR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	DL-Racemate
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.