Description

Sodium (Z)-3-Cyano-4-Ethoxy-1,1,1-Trifluoro-4-Oxobut-2-En-2-Olate is a high-value, organofluorine building block and synthetic intermediate. Its core value lies in providing a reactive trifluoromethylated enolate moiety, which is crucial for constructing complex molecules in advanced pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists working in medicinal chemistry, particularly for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates containing trifluoromethyl groups, which enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the CF3 group can improve activity and environmental profile.
• Material Science Research: Serves as a precursor for specialty fluorinated polymers or organic electronic materials.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed reactions to introduce complex fluorinated fragments.
• Process Chemistry: Investigated for scalable routes to fluorinated active pharmaceutical ingredients (APIs).
• Academic Research: A valuable reagent for methodological studies in organofluorine chemistry and asymmetric synthesis.

Basic Information

Item	Details
Product Name	Sodium (Z)-3-Cyano-4-Ethoxy-1,1,1-Trifluoro-4-Oxobut-2-En-2-Olate
CAS No.	1311283-96-1
Molecular Formula	C9H5F3NNaO3
Molecular Weight	255.12 g/mol
Synonyms	Sodium 2-Cyano-3-ethoxy-4,4,4-trifluoro-3-buten-2-olate; (Z)-Sodium 3-Cyano-4-ethoxy-1,1,1-trifluoro-4-oxobut-2-en-2-olate; Sodium 4-Ethoxy-1,1,1-trifluoro-3-oxo-2-buten-2-olate-3-carbonitrile; Ethyl 2-Cyano-3,3,3-trifluoro-2-propenoate Sodium Enolate; Trifluoromethylated Cyanoacetate Enolate Sodium Salt
EINECS	Contact for details

Quality Control

Our Sodium (Z)-3-Cyano-4-Ethoxy-1,1,1-Trifluoro-4-Oxobut-2-En-2-Olate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator to prevent degradation. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.