Description

Boronic Acid, B-[2-[(2-Fluorophenyl)Methoxy]Phenyl]- is a specialized organoboron compound featuring a biphenyl ether scaffold with a fluorinated aromatic ring. This compound is a critical synthetic intermediate, valued for its role in the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for constructing carbon-carbon bonds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and sensors.
• Chemical Synthesis: Essential reagent in palladium-catalyzed cross-coupling reactions to form biaryl structures prevalent in many functional molecules.
• Academic & R&D: Employed in university and institutional laboratories for methodological development and exploring new chemical spaces.
• Ligand & Catalyst Development: Potential use in the design of novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Boronic Acid, B-[2-[(2-Fluorophenyl)Methoxy]Phenyl]-
CAS No.	1311165-78-2
Molecular Formula	C13H12BFO3
Molecular Weight	246.05 g/mol
Synonyms	[2-[(2-Fluorophenyl)methoxy]phenyl]boronic acid; 2-[(2-Fluorobenzyl)oxy]phenylboronic acid; B-[2-[(2-Fluorophenyl)methoxy]phenyl]boronic acid; (2-((2-Fluorobenzyl)oxy)phenyl)boronic acid; 2-Fluorobenzyl 2-boronophenol ether; 2-(2-Fluorobenzyloxy)benzeneboronic acid; 2-[(2-Fluorobenzyl)oxy]benzeneboronic acid
EINECS	Contact for details

Quality Control

Our Boronic Acid, B-[2-[(2-Fluorophenyl)Methoxy]Phenyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, and can support development projects with custom purity grades, including research, development, and cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.