Description

(R)-Boc-2-Amino-3-Ethyl-Pentanoic Acid CAS NO 1310680-39-7 is a high-purity, non-natural amino acid derivative featuring a chiral center and a tert-butoxycarbonyl (Boc) protecting group. This compound is a critical chiral building block for the synthesis of complex peptides and peptidomimetics, enabling precise control over stereochemistry in pharmaceutical research. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Peptide Synthesis: Serves as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS).
• Peptidomimetic Design: Used to create peptide analogs with enhanced metabolic stability and bioavailability for therapeutic applications.
• Chemical Biology Research: Employed in the study of protein-protein interactions and the development of enzyme inhibitors.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in stereoselective organic synthesis.
• Reference Standard: Suitable for use as an analytical standard in quality control and method development for related compounds.

Basic Information

Product Name	(R)-Boc-2-Amino-3-Ethyl-Pentanoic Acid
CAS No.	1310680-39-7
Molecular Formula	C₁₂H₂₃NO₄
Molecular Weight	245.32 g/mol
Synonyms	(R)-2-[(tert-Butoxycarbonyl)amino]-3-ethylpentanoic acid; (R)-Boc-Amino-3-ethylpentanoic Acid; Boc-D-Homoisoleucine; Boc-(R)-2-Amino-3-ethylpentanoic acid; (R)-3-Ethyl-2-((tert-butoxycarbonyl)amino)pentanoic acid; N-Boc-D-2-Amino-3-ethylpentanoic acid; N-(tert-Butoxycarbonyl)-D-homoisoleucine
EINECS	Contact for details

Quality Control

Our (R)-Boc-2-Amino-3-Ethyl-Pentanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.