Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl 5,5-Dimethyl-L-Pro is a specialized, high-purity amino acid derivative designed for advanced synthetic chemistry. This compound is a critical building block in the synthesis of complex peptides and peptidomimetics, offering enhanced steric control and stability. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, process development, and the production of active pharmaceutical ingredients (APIs).

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected proline analog for the controlled assembly of therapeutic peptides.
• Peptidomimetic Drug Design: To introduce conformational constraints and improve metabolic stability in novel drug candidates.
• Pharmaceutical Intermediate: In the multi-step synthesis of complex target molecules for preclinical and clinical studies.
• Biochemical Research: For studying enzyme-substrate interactions and protein structure-function relationships.
• Process Chemistry: Scaling up the production of key intermediates under current Good Manufacturing Practice (cGMP) guidelines.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl 5,5-Dimethyl-L-Pro
CAS No.	1310680-23-9
Molecular Formula	C22H23NO4
Molecular Weight	365.42 g/mol
Synonyms	Fmoc-5,5-dimethyl-L-proline; Fmoc-Dmp-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-5,5-dimethyl-L-proline; 1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-5,5-dimethyl-L-proline; Fmoc-5,5-Dimethylproline; N-Fmoc-5,5-dimethyl-L-proline; (2S)-1-(9H-Fluoren-9-ylmethoxycarbonyl)-5,5-dimethylpyrrolidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of (9H-Fluoren-9-Yl)Methoxy]Carbonyl 5,5-Dimethyl-L-Pro adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.