Description

1-Bromo-3-Ethoxy-5-(Trifluoromethyl)Benzene is a high-purity, multi-functional aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring bromine, ethoxy, and trifluoromethyl substituents, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the benzene core provides a scaffold for bioactive molecules.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing aromatic compounds used in electronic display technologies and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Material Research: Employed in the research and development of specialty polymers, coatings, and advanced organic frameworks with specific electronic or surface properties.
• Chemical Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1-Bromo-3-Ethoxy-5-(Trifluoromethyl)Benzene
CAS No.	1310416-62-6
Molecular Formula	C9H8BrF3O
Molecular Weight	269.06 g/mol
Synonyms	3-Bromo-5-ethoxybenzotrifluoride; 5-Bromo-3-ethoxybenzotrifluoride; 1-Bromo-3-ethoxy-5-(trifluoromethyl)benzene; 3-Ethoxy-5-(trifluoromethyl)bromobenzene; 5-(Trifluoromethyl)-3-ethoxybromobenzene; Benzene, 1-bromo-3-ethoxy-5-(trifluoromethyl)-; 3-Bromo-5-ethoxy-α,α,α-trifluorotoluene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Ethoxy-5-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.