Description

4-Ethoxy-2,6-Difluorophenylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in its role as a key intermediate for the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex difluorinated biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic structures.
• Material Science: Serves as a monomer or building block for creating advanced polymers, liquid crystals, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: Primarily employed as a versatile boronic acid coupling partner for palladium-catalyzed C-C bond formation with aryl halides.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and compound libraries.
• Ligand Synthesis: Potential use in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Ethoxy-2,6-Difluorophenylboronic Acid
CAS No.	1310403-94-1
Molecular Formula	C8H9BF2O3
Molecular Weight	201.97 g/mol
Synonyms	2,6-Difluoro-4-ethoxyphenylboronic Acid; (4-Ethoxy-2,6-difluorophenyl)boronic Acid; 4-Ethoxy-2,6-difluorobenzeneboronic Acid; B-(4-Ethoxy-2,6-difluorophenyl)boronic Acid; 1310403-94-1; 4-Ethoxy-2,6-difluorophenyl-B(OH)2; 2,6-Difluoro-4-ethoxybenzeneboronic Acid
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-2,6-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.