Description

5-Bromo-2-Chloro-3-(Trifluoromethyl)-Phenylboronic Acid is a high-purity, multi-functional boronic acid derivative serving as a critical building block in modern synthetic chemistry. Its value lies in enabling the precise construction of complex molecular architectures through reliable cross-coupling reactions. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex, fluorinated biaryl compounds targeted in drug discovery programs.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, leveraging the unique properties of the trifluoromethyl and halogen substituents.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialized polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed for constructing novel bidentate or tridentate ligands used in homogeneous catalysis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes, benefiting from its boronic acid functionality.

Basic Information

Product Name	5-Bromo-2-Chloro-3-(Trifluoromethyl)-Phenylboronic Acid
CAS No.	1310403-90-7
Molecular Formula	C7H4BBrClF3O2
Molecular Weight	303.27 g/mol
Synonyms	[5-Bromo-2-Chloro-3-(Trifluoromethyl)Phenyl]Boronic Acid; (5-Bromo-2-Chloro-3-(Trifluoromethyl)Phenyl)Boronic Acid; 2-Chloro-5-Bromo-3-(Trifluoromethyl)Benzeneboronic Acid; 5-Bromo-2-Chloro-α,α,α-Trifluoro-m-Tolylboronic Acid; 3-Borono-5-Bromo-2-Chlorobenzotrifluoride
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-3-(Trifluoromethyl)-Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance in demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.