Description

3-Chloro-2,4-Difluorophenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. This compound matters for its critical role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heteroaryl structures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) with complex halogenated aromatic cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific halogen-substituted phenyl groups.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs serving the global life sciences market.

Basic Information

Product Name	3-Chloro-2,4-Difluorophenylboronic Acid
CAS No.	1310384-18-9
Molecular Formula	C6H4BClF2O2
Molecular Weight	191.36 g/mol
Synonyms	(3-Chloro-2,4-difluorophenyl)boronic acid; 3-Chloro-2,4-difluorobenzeneboronic acid; Boronic acid, B-(3-chloro-2,4-difluorophenyl)-; 2,4-Difluoro-3-chlorophenylboronic acid; 1310384-18-9; 3-Cl-2,4-F2-PhB(OH)2
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,4-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting industry standards. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee supply reliability and product consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.