Description

2-Bromo-4-(Trifluoromethyl)Phenylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its primary commercial value lies in enabling the precise construction of complex molecules through palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is particularly critical for researchers and manufacturers in the pharmaceutical and agrochemical industries who require the introduction of a bromo-trifluoromethylphenyl moiety into target structures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the biological activity imparted by the trifluoromethyl group.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials, liquid crystals, and polymers with specific optoelectronic properties.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Bromo-4-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1310383-25-5
Molecular Formula	C7H5BBrF3O2
Molecular Weight	267.83 g/mol
Synonyms	[2-Bromo-4-(trifluoromethyl)phenyl]boronic acid; (2-Bromo-4-trifluoromethylphenyl)boronic acid; 2-Bromo-4-trifluoromethylbenzeneboronic acid; B-(2-Bromo-4-(trifluoromethyl)phenyl)boronic acid; 2-Bromo-α,α,α-trifluoro-p-tolueneboronic acid; Boronic acid, B-[2-bromo-4-(trifluoromethyl)phenyl]-; 1310383-25-5
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.