Description

5-Bromo-1,3-Difluoro-2-Isopropoxybenzene is a high-purity, multi-functional halogenated aromatic ether building block. This compound is valued for its unique substitution pattern, which makes it a critical intermediate in the synthesis of complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorinated aromatic core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the bromo and fluoro substituents enhance biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological mechanisms and diagnostics.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and fine chemical companies for bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	5-Bromo-1,3-Difluoro-2-Isopropoxybenzene
CAS No.	1309933-98-9
Molecular Formula	C9H9BrF2O
Molecular Weight	251.07 g/mol
Synonyms	1-Bromo-3,5-difluoro-2-isopropoxybenzene; 2-Isopropoxy-1-bromo-3,5-difluorobenzene; 2-Bromo-4,6-difluorophenyl isopropyl ether; 5-Bromo-1,3-difluoro-2-(1-methylethoxy)benzene; Benzene, 5-bromo-1,3-difluoro-2-(1-methylethoxy)-; 1309933-98-9; 5-Br-1,3-F2-2-iPrO-Benzene (abbrev.)
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,3-Difluoro-2-Isopropoxybenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.