Description

5-Bromo-2-Butoxy-1,3-Difluorobenzene is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. This compound is valued for its unique substitution pattern, offering a reactive bromine site and a stable butoxy ether linkage, which makes it a versatile intermediate for constructing complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for applications in cross-coupling reactions and as a precursor for liquid crystals or organic electronic materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorobenzene core with orthogonal reactivity.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogen and fluorine substituents for bioactivity.
• Material Science Precursor: Serves as a monomer or intermediate in the production of specialty polymers, liquid crystals, and organic semiconductors for electronic applications.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Chemical Research & Development: Employed in academic and industrial labs as a versatile scaffold for exploring new synthetic methodologies and creating compound libraries.
• Fluorine Chemistry Studies: Acts as a model compound for studying the electronic and steric effects of fluorine atoms in aromatic systems.

Basic Information

Product Name	5-Bromo-2-Butoxy-1,3-Difluorobenzene
CAS No.	1309932-85-1
Molecular Formula	C10H11BrF2O
Molecular Weight	265.10 g/mol
Synonyms	1-Bromo-4-butoxy-2,6-difluorobenzene; 2,6-Difluoro-4-bromobutoxybenzene; 5-Bromo-1,3-difluoro-2-butoxybenzene; 4-Bromo-2,6-difluorophenyl butyl ether; Butyl 4-bromo-2,6-difluorophenyl ether; 1309932-85-1; 5-Bromo-2-butoxy-1,3-difluorobenzene
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Butoxy-1,3-Difluorobenzene is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system supports traceability and is designed to meet the rigorous standards of cGMP and ISO-guided environments for research and commercial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.