Description

Methyl 2-{[(3,4-Difluorophenyl)Methyl]Amino}Acetate Hydrochloride is a high-purity, synthetically derived chemical intermediate of significant importance in modern pharmaceutical research and development. Its core value lies in its role as a key building block for constructing complex molecules, particularly in the synthesis of active pharmaceutical ingredients (APIs) targeting neurological and metabolic pathways. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors who require reliable, high-quality intermediates for their synthetic workflows.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel drug candidates, particularly those with fluorinated aromatic systems.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the research and process development of APIs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and pesticides, leveraging the stability imparted by the difluorophenyl group.
• Chemical Biology & Proteomics: Employed as a specialty reagent for modifying peptides or creating molecular probes to study biological systems.
• Material Science Research: Potential use as a monomer or functionalization agent in the development of advanced polymers with specific properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and scale-up services for the life sciences industry.

Basic Information

Product Name	Methyl 2-{[(3,4-Difluorophenyl)Methyl]Amino}Acetate Hydrochloride
CAS No.	1305712-66-6
Molecular Formula	C11H12F2NO2 • HCl
Molecular Weight	263.68 g/mol (Free base: 227.21 g/mol)
Synonyms	Methyl N-[(3,4-Difluorophenyl)methyl]glycinate Hydrochloride; 2-[[(3,4-Difluorophenyl)methyl]amino]acetic acid methyl ester hydrochloride; Methyl (3,4-Difluorobenzylamino)acetate HCl; Glycine, N-[(3,4-difluorophenyl)methyl]-, methyl ester, hydrochloride; Methyl 2-((3,4-difluorobenzyl)amino)acetate hydrochloride
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-{[(3,4-Difluorophenyl)Methyl]Amino}Acetate Hydrochloride is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure it meets the high-purity standards required for research and development. Our products are characterized using advanced techniques including HPLC, NMR, and MS to confirm identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.