Description

3-(2-Chloro-5-Thiazolylmethyl)Tetrahydro-5-Methyl-D3-n-Nitro-4H-1,3,5-Oxadiazin-4-Imine CAS NO 1294048-82-0 is a high-purity, deuterated chemical intermediate of significant interest in advanced research and development. Its complex heterocyclic structure, featuring a thiazole ring and a nitro-substituted oxadiazine core, makes it a valuable building block for creating novel compounds. This product is primarily targeted at the pharmaceutical and agrochemical industries, where it is used in the synthesis of deuterated active ingredients for drug discovery, metabolic studies, and the development of new crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of deuterated drug candidates, enhancing metabolic stability and pharmacokinetic profiles in preclinical research.
• Agrochemical Research: Used in developing novel, deuterated pesticides and herbicides to study efficacy and environmental fate.
• Metabolic Labeling: Serves as a stable isotope (Deuterium, D3) label in mass spectrometry-based metabolic studies and tracing experiments.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies by providing a deuterated analog of lead compounds.
• Chemical Synthesis: A specialized intermediate for constructing complex heterocyclic frameworks in organic and process chemistry.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	3-(2-Chloro-5-Thiazolylmethyl)Tetrahydro-5-Methyl-D3-n-Nitro-4H-1,3,5-Oxadiazin-4-Imine
CAS No.	1294048-82-0
Molecular Formula	C9H8D3ClN4O3S
Molecular Weight	306.75 g/mol (for deuterated form)
Synonyms	3-[(2-Chloro-1,3-thiazol-5-yl)methyl]-5-methyl-D3-tetrahydro-5-nitro-4H-1,3,5-oxadiazin-4-imine; 5-Methyl-D3-3-[(2-chloro-5-thiazolyl)methyl]tetrahydro-5-nitro-4H-1,3,5-oxadiazin-4-imine; Deuterated Thiazolylmethyl Oxadiazinimine; (2-Chloro-thiazol-5-ylmethyl)-5-methyl-D3-tetrahydro-5-nitro-4H-[1,3,5]oxadiazin-4-imine; D3-Labeled Nitro-oxadiazine Intermediate; CAS 1294048-82-0.
EINECS	Contact for details

Quality Control

Our 3-(2-Chloro-5-Thiazolylmethyl)Tetrahydro-5-Methyl-D3-n-Nitro-4H-1,3,5-Oxadiazin-4-Imine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and deuterium enrichment analysis, to ensure it meets precise customer specifications. A detailed Certificate of Analysis (COA) documenting identity, purity, and isotopic enrichment is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.