Description

Methylene-Bis Paroxetine (CAS NO 1292846-10-6) is a key pharmaceutical intermediate primarily used in the synthesis of advanced active pharmaceutical ingredients (APIs). This compound is critical for ensuring the structural integrity and efficacy of final drug products in the neuropharmacology sector. It is essential for manufacturers and R&D facilities focused on developing and producing high-purity, complex therapeutic agents.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of paroxetine-related APIs and novel drug candidates.
• Neuropharmacology Research: Serves as a crucial building block in R&D for central nervous system (CNS) targeting therapeutics.
• Process Chemistry: Used in scale-up and optimization of manufacturing routes for complex organic molecules.
• Reference Standard: Acts as a high-purity standard for analytical method development and quality control in pharmaceutical labs.
• Custom Synthesis: A starting material for the preparation of specialized derivatives and analogs in medicinal chemistry.

Basic Information

Product Name	Methylene-Bis Paroxetine
CAS No.	1292846-10-6
Molecular Formula	C34H38F2N2O6
Molecular Weight	608.68 g/mol
Synonyms	Bis-Paroxetine Methylene Derivative; 1,1'-[Methylenebis(oxy)]bis[3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine]; Paroxetine Dimer; 4,4'-(Methylenedioxy)bis(paroxetine); N,N'-Methylenebis(paroxetine); MB-Paroxetine; (3S,4R)-3-(((1,3-Benzodioxol-5-yl)oxy)methyl)-4-(4-fluorophenyl)-1-((((3S,4R)-3-(((1,3-benzodioxol-5-yl)oxy)methyl)-4-(4-fluorophenyl)piperidin-1-yl)methoxy)methyl)piperidine
EINECS	Contact for details

Quality Control

Our Methylene-Bis Paroxetine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.