Description

6-Aminoazepan-2-One Hydrochloride is a high-purity organic salt of significant interest in advanced pharmaceutical synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and process development programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly those targeting neurological and metabolic disorders.
• API Development: Used in research and process chemistry for constructing the core scaffolds of new therapeutic candidates.
• Peptidomimetic Research: Serves as a constrained amino acid analog in the design of peptide-like compounds with enhanced metabolic stability.
• Chemical Biology Probes: Employed in the synthesis of specialized probes for studying enzyme mechanisms and protein interactions.
• Asymmetric Synthesis: Acts as a precursor for chiral auxiliaries or catalysts used in stereoselective transformations.

Basic Information

Product Name	6-Aminoazepan-2-One Hydrochloride
CAS No.	1292369-18-6
Molecular Formula	C6H13N2O·HCl
Molecular Weight	164.64 g/mol (Free base: 129.18 g/mol)
Synonyms	6-Amino-2-azepanone hydrochloride; 2-Azepanone, 6-amino-, hydrochloride; 6-Aminocaprolactam hydrochloride; (6-Aminoazepan-2-one) hydrochloride; 6-Amino-ε-caprolactam HCl; 6-Aminohexanoic acid lactam hydrochloride; 6-Amino-2-oxoazepane hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Aminoazepan-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP starting material applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. The container should be kept tightly sealed in a desiccator after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.