Description

3-Ethynyloxetane is a highly versatile and reactive heterocyclic building block containing both an oxetane ring and an ethynyl (acetylene) functional group. This unique bifunctional structure makes it a critical intermediate for advanced material science and pharmaceutical research, enabling the synthesis of complex molecular architectures. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for applications in click chemistry, polymer cross-linking, and as a key synthon for novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of novel drug candidates, particularly in fragment-based drug discovery and PROTAC development.
• Click Chemistry Reagent: The terminal alkyne group enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and material labeling.
• Polymer & Material Science: Used as a monomer or cross-linking agent to create polymers with tailored properties, such as high thermal stability or specific refractive indices.
• Agrochemical Synthesis: Employed in the research and development of new herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Materials: Acts as a precursor for synthesizing advanced organic electronic materials due to its rigid-rod potential and functional handles.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists exploring new reaction methodologies and complex natural product analogs.

Basic Information

Product Name	3-Ethynyloxetane
CAS No.	1290541-38-6
Molecular Formula	C5H6O
Molecular Weight	82.10 g/mol
Synonyms	3-Ethynyloxetane; Oxetane, 3-ethynyl-; 3-Ethynyl-1-oxacyclobutane; 3-Oxetanylacetylene; 3-Acetylenyloxetane; 3-(Ethynyl)oxetane; 1290541-38-6
EINECS	Contact for details

Quality Control

Our 3-Ethynyloxetane is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (GC, HPLC, NMR) to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its reactive functional groups, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability and to minimize potential polymerization or degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.