Description

2-(Methoxymethyl)Azetidine is a versatile azetidine derivative, a four-membered nitrogen-containing heterocycle, serving as a crucial building block in advanced organic synthesis. Its unique structure, featuring a methoxymethyl side chain, makes it a valuable intermediate for constructing complex molecules with specific stereochemistry and functionality. This compound is particularly sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in developing protease inhibitors, kinase inhibitors, and other small-molecule therapeutics.
• Agrochemical Research: Used in constructing novel scaffolds for herbicides, fungicides, and insecticides, leveraging the azetidine ring's bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of functional polymers and dendrimers where the azetidine ring contributes to specific material properties.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological pathways and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high-purity, specialized heterocyclic intermediates.

Basic Information

Product Name	2-(Methoxymethyl)Azetidine
CAS No.	1290136-94-5
Molecular Formula	C5H11NO
Molecular Weight	101.15 g/mol
Synonyms	2-(Methoxymethyl)azetidine; Azetidine, 2-(methoxymethyl)-; 2-Methoxymethyl-azetidine; 2-(Methoxymethyl)azacyclobutane; NSC 106021; 1290136-94-5; (Azetidin-2-yl)methanol methyl ether
EINECS	Contact for details

Quality Control

Every batch of 2-(Methoxymethyl)Azetidine is produced and tested under a strict Quality Management System. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, typically including results from GC, HPLC, NMR, and Karl Fischer titration. Our quality protocols are designed to support cGMP and ISO-guided applications where documentation and traceability are paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.