Description

2-(1-Hydroxycyclobutyl)Acetonitrile is a versatile and high-purity chemical intermediate featuring a unique cyclobutanol-substituted nitrile structure. This compound is valued for its role as a critical building block in the synthesis of complex organic molecules, offering a reactive handle for further functionalization. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and advanced material science.

Application

This specialized intermediate is engineered for high-value synthetic applications. Key uses include:

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides and fungicides with enhanced efficacy.
• Material Science Research: Utilized in the development of advanced polymers and liquid crystals due to its rigid cyclobutyl framework.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring high-purity, complex nitrile derivatives.

Basic Information

Product Name	2-(1-Hydroxycyclobutyl)Acetonitrile
CAS No.	1289648-06-1
Molecular Formula	C6H9NO
Molecular Weight	111.14 g/mol
Synonyms	1-Hydroxycyclobutaneacetonitrile; (1-Hydroxycyclobutyl)acetonitrile; 2-(1-Hydroxycyclobutyl)ethanenitrile; Cyclobutanol, 1-cyanomethyl-; Acetonitrile, 2-(1-hydroxycyclobutyl)-; 1289648-06-1; 2-(Hydroxycyclobutyl)acetonitrile
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our chemical intermediates. Production of 2-(1-Hydroxycyclobutyl)Acetonitrile adheres to current Good Manufacturing Practices (cGMP) where applicable, ensuring batch-to-batch consistency and traceability. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the exacting standards of pharmaceutical and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, maintaining the product at 2-8°C under an inert atmosphere is recommended to preserve stability. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.