Description

Bis(2-Trifluoromethylphenyl)(3-Sulfonatophenyl)Phosphine, Sodium Salt is a water-soluble, sulfonated phosphine ligand, a key component in modern transition metal catalysis. Its primary value lies in enabling efficient aqueous-phase catalytic reactions, offering significant advantages in separation and environmental friendliness over traditional organic-phase systems. This compound is essential for researchers and manufacturers in the pharmaceutical, fine chemical, and agrochemical industries who require robust and recyclable catalysts for cross-coupling, hydrogenation, and hydroformylation processes. Its unique structure provides excellent stability and activity for precious metal catalysts like palladium and rhodium.

Application

• Aqueous-Phase Catalysis: As a ligand for palladium, rhodium, and ruthenium catalysts in cross-coupling (Suzuki, Heck), hydrogenation, and hydroformylation reactions conducted in water.
• Pharmaceutical Intermediates: Enabling the synthesis of complex drug molecules through efficient and cleaner catalytic processes that simplify product isolation.
• Homogeneous Catalyst Recovery: Facilitating the recycling and reuse of expensive transition metal catalysts via aqueous/organic biphasic systems or membrane filtration.
• Fine Chemical Synthesis: Used in the production of specialty chemicals, flavors, and fragrances where high selectivity and mild reaction conditions are required.
• Agrochemical Manufacturing: Applied in the catalytic synthesis of advanced pesticides and herbicides.
• Polymer Chemistry: Serving as a ligand in catalytic polymerization reactions to produce specialized polymers.
• Academic & Industrial R&D: A valuable tool for developing new synthetic methodologies and catalytic processes in both university and corporate research laboratories.

Basic Information

Product Name	Bis(2-Trifluoromethylphenyl)(3-Sulfonatophenyl)Phosphine, Sodium Salt
CAS No.	1289463-93-9
Molecular Formula	C20H11F6NaO3PS
Molecular Weight	505.31 g/mol
Synonyms	Sodium 3-(Bis[2-(trifluoromethyl)phenyl]phosphino)benzenesulfonate; (3-Sulfonatophenyl)bis[2-(trifluoromethyl)phenyl]phosphine Sodium Salt; Sodium Trisulfonated Triphenylphosphine Derivative; Sulfonated Phosphine Ligand; Water-Soluble TPPTS Analog; Na-TPPTS (CF3)2; Bis(2-Trifluoromethylphenyl)(3-Sulfonatophenyl)Phosphine Sodium Salt; CAS 1289463-93-9
EINECS	Contact for details

Quality Control

Our production of Bis(2-Trifluoromethylphenyl)(3-Sulfonatophenyl)Phosphine, Sodium Salt adheres to stringent internal quality standards to ensure batch-to-batch consistency and high catalytic performance. Each lot is characterized by advanced analytical techniques including NMR (¹H, ¹³C, ³¹P), HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support cGMP and ISO 9001 compliant manufacturing for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider keeping the container under an inert atmosphere (argon or nitrogen) in a desiccator. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (NMR)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.