Description

Bis(3,5-Di-Trifluoromethylphenyl)(3-Sulfonatophenyl)Phosphine, Sodium Salt is a highly specialized, water-soluble phosphine ligand designed for advanced catalytic applications. Its core value lies in enabling efficient, high-yield cross-coupling reactions in aqueous or biphasic systems, offering significant advantages in process simplification and environmental friendliness. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require robust, recyclable catalysts for complex synthesis.

Application

• As a water-soluble ligand for transition metal catalysis (e.g., palladium, rhodium) in aqueous-phase reactions.
• Enabling Suzuki-Miyaura and Heck cross-coupling reactions in biphasic or purely aqueous media for pharmaceutical intermediate synthesis.
• Facilitating catalyst recovery and recycling in industrial processes, improving cost-efficiency and reducing metal contamination.
• Use in asymmetric hydrogenation and other chiral inductions for the production of enantiomerically pure compounds.
• Application in academic and industrial research for developing new sustainable catalytic methodologies.
• Potential use in polymerization catalysts and material science for creating functional polymers.

Basic Information

Product Name	Bis(3,5-Di-Trifluoromethylphenyl)(3-Sulfonatophenyl)Phosphine, Sodium Salt
CAS No.	1289463-91-7
Molecular Formula	C21H9F12NaO3PS
Molecular Weight	638.30 g/mol
Synonyms	Sodium 3-(Bis(3,5-bis(trifluoromethyl)phenyl)phosphino)benzenesulfonate; Tris(3,5-bis(trifluoromethyl)phenyl)phosphine sodium sulfonate derivative; Sulfonated Tris(3,5-bis(trifluoromethyl)phenyl)phosphine Sodium Salt; Water-soluble TPPTS analogue (fluorinated); 3-(Bis(3,5-bis(trifluoromethyl)phenyl)phosphanyl)benzenesulfonic acid sodium salt; Sodium 3-(di(3,5-di(trifluoromethyl)phenyl)phosphino)benzenesulfonate; Fluorinated sulfonated phosphine ligand; Na-TPPTS-F12
EINECS	Contact for details

Quality Control

Our Bis(3,5-Di-Trifluoromethylphenyl)(3-Sulfonatophenyl)Phosphine, Sodium Salt is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation. Comprehensive Certificates of Analysis (COA) detailing purity, residual solvents, and moisture content are provided to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.