Description

Bis(4-Trifluoromethylphenyl)(3-Sulfonatophenyl)Phosphine, Sodium Salt is a water-soluble, sulfonated phosphine ligand, a key specialty chemical for advanced catalytic processes. Its value lies in enabling efficient, high-yield reactions in aqueous or biphasic systems, offering significant advantages in catalyst recovery and process sustainability. This compound is essential for R&D and production chemists in the pharmaceutical, fine chemical, and material science industries, particularly for cross-coupling and hydrogenation reactions.

Application

• Aqueous-Phase Catalysis: As a key ligand for transition metal catalysts (e.g., Pd, Rh) in water, enabling environmentally friendly synthesis.
• Pharmaceutical Intermediates: Facilitating critical cross-coupling reactions (Suzuki, Heck) for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used in the production of high-value specialty chemicals, agrochemicals, and flavors & fragrances where catalyst separation is crucial.
• Hydrogenation Reactions: Serving as a ligand for asymmetric hydrogenation catalysts to produce chiral intermediates.
• Material Science: Potential application in the surface modification of nanoparticles and the synthesis of functional polymers.
• Homogeneous Catalyst Recovery: Enabling efficient catalyst recycling in biphasic systems, improving process economics.

Basic Information

Product Name	Bis(4-Trifluoromethylphenyl)(3-Sulfonatophenyl)Phosphine, Sodium Salt
CAS No.	1289463-87-1
Molecular Formula	C20H11F6NaO3PS
Molecular Weight	505.31 g/mol
Synonyms	Sodium 3-(Bis(4-(trifluoromethyl)phenyl)phosphino)benzenesulfonate; Trisulfonated Triphenylphosphine Derivative; Sulfonated Phosphine Ligand; Water-Soluble TPPTS Analog; (3-Sulfonatophenyl)bis[4-(trifluoromethyl)phenyl]phosphine Sodium Salt; Na-TPPTCF3; BTPPS
EINECS	Contact for details

Quality Control

Our production of Bis(4-Trifluoromethylphenyl)(3-Sulfonatophenyl)Phosphine, Sodium Salt adheres to stringent internal quality standards to ensure batch-to-batch consistency and high catalytic performance. Every lot is characterized using advanced analytical techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and assay is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Elemental Analysis	Conforms to theoretical values

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.