Description

Bis(3-Sulfonatophenyl)(3,5-Di-Trifluoromethylphenyl)Phosphine, Disodium Salt Monohydrate, Min. 97% Danphos (Water Soluble) is a highly specialized, water-soluble phosphine ligand designed for advanced catalytic applications. Its core value lies in enabling efficient transition metal-catalyzed reactions in aqueous or biphasic media, offering significant advantages in catalyst recovery and process sustainability. This compound is essential for R&D and production chemists in the pharmaceutical, fine chemical, and agrochemical industries who require robust, recyclable catalytic systems for cross-coupling and hydrogenation reactions. The CAS number for this compound is provided in the table below.

Application

• Aqueous-Phase Catalysis: As a key ligand for palladium, rhodium, and ruthenium catalysts in cross-coupling (Suzuki, Heck, Sonogashira) and hydrogenation reactions performed in water.
• Biphasic System Development: Enables the creation of water/organic solvent biphasic systems for facile product separation and catalyst recycling.
• Pharmaceutical Intermediate Synthesis: Used in the synthesis of complex drug molecules where aqueous compatibility and catalyst removal are critical for purity.
• Fine Chemical Manufacturing: Facilitates greener synthetic routes for high-value specialty chemicals, reducing organic solvent waste.
• Homogeneous Catalyst Immobilization: Serves as a ligand in systems designed for catalyst recovery via aqueous extraction or membrane filtration.
• Agrochemical Research: Applied in the development of novel active ingredients using sustainable catalytic methodologies.
• Academic & Industrial R&D: A valuable tool for exploring new catalytic transformations and process intensification in aqueous environments.

Basic Information

Item	Detail
Product Name	Bis(3-Sulfonatophenyl)(3,5-Di-Trifluoromethylphenyl)Phosphine, Disodium Salt Monohydrate, Min. 97% Danphos (Water Soluble)
CAS No.	1289463-82-6
Molecular Formula	C20H11F6Na2O7PS2 • H2O
Molecular Weight	Contact for details
Synonyms	Danphos; 3,3',5,5'-Tetrakis(trifluoromethyl)-[1,1'-biphenyl]-2,2'-diylbis[diphenylphosphine] disulfonate disodium salt (related parent compound); Water-soluble TPPTS analog; Sulfonated phosphine ligand; BISBIS sulfonate; (3,5-Bis(trifluoromethyl)phenyl)bis(3-sulfophenyl)phosphine disodium salt; Tris(3-sulfonatophenyl)phosphine trisodium salt analog; Aqueous-phase ligand.
EINECS	Contact for details

Quality Control

Every batch of our Bis(3-Sulfonatophenyl)(3,5-Di-Trifluoromethylphenyl)Phosphine, Disodium Salt Monohydrate is produced and tested under a strict quality management system. We guarantee a minimum purity of 97% (by HPLC), with comprehensive testing for identity, purity, residual solvents, and moisture content. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and must be stored in a cool, dry place. For long-term stability, store at 2-8°C under an inert atmosphere such as argon or nitrogen. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
Water Content (KF)	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
pH (1% aqueous solution)	6.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.