Description

Clopidogrel Metabolite Ii CAS NO 1287430-40-3 is a key intermediate and reference standard in the synthesis and analytical profiling of the antiplatelet drug clopidogrel. This compound is critical for pharmaceutical research and development, enabling precise quality control and metabolic studies. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and analytical laboratories involved in API production, bioequivalence testing, and regulatory compliance.

Application

• Primary reference standard for the quality control of Clopidogrel API and finished dosage forms.
• Critical intermediate in the research-scale synthesis of Clopidogrel and its derivatives.
• Metabolite standard for in-vitro and in-vivo pharmacokinetic and pharmacodynamic studies.
• Analytical standard for method development and validation in HPLC and LC-MS/MS assays.
• Impurity profiling and characterization to meet ICH guidelines for pharmaceutical impurities.
• Use in bioanalytical studies for drug metabolism and excretion pathways.
• Material for calibration in clinical diagnostic testing related to antiplatelet therapy monitoring.

Basic Information

Product Name	Clopidogrel Metabolite Ii
CAS No.	1287430-40-3
Molecular Formula	C16H16ClNO2S
Molecular Weight	321.82 g/mol
Synonyms	Clopidogrel Carboxylic Acid; Clopidogrel Metabolite (SR26334); 2-{2-(2-Chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetoxy}acetic Acid; (2-Chlorophenyl)(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)acetic Acid Carboxymethyl Ester; Clopidogrel Acid; Clopidogrel Inactive Metabolite; SR 26334
EINECS	Contact for details

Quality Control

Our Clopidogrel Metabolite Ii is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC purity assay, residual solvent analysis, and identity confirmation (IR, MS) to ensure it meets the stringent requirements for pharmaceutical reference standards. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.