Description

Albendazole-D7 is a deuterated analog of the broad-spectrum anthelmintic drug Albendazole, specifically labeled with seven deuterium atoms. This stable isotope-labeled compound is an essential reference standard and internal standard for precise quantitative analysis in pharmaceutical research and development. It is primarily used by analytical chemists and researchers in the pharmaceutical, contract research organization (CRO), and regulatory testing sectors to ensure accurate pharmacokinetic, metabolic, and bioanalytical studies, supporting drug development and quality control.

Application

• Internal Standard for LC-MS/MS: Serves as a critical, non-interfering internal standard for the accurate quantification of Albendazole and its metabolites in complex biological matrices using liquid chromatography-tandem mass spectrometry.
• Pharmacokinetic & Metabolism Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research due to its nearly identical chemical properties with distinct mass.
• Bioanalytical Method Development & Validation: Used as a reference material to develop, validate, and ensure the robustness and regulatory compliance of analytical methods for therapeutic drug monitoring.
• Drug Impurity Profiling & Degradation Studies: Acts as a tracer in stability-indicating methods to identify and quantify potential impurities or degradation products of Albendazole.
• Certified Reference Material (CRM): Provides a traceable and reliable standard for instrument calibration and quality assurance in analytical laboratories to meet GLP and GMP requirements.

Basic Information

Product Name	Albendazole-D7
CAS No.	1287076-43-0
Molecular Formula	C12H8D7N3O2S
Molecular Weight	265.37 g/mol
Synonyms	Albendazole-d7; Methyl [5-(propylthio)-1H-benzimidazol-2-yl]carbamate-d7; (5-(Propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester-d7; Albendazole (methyl-d3, propyl-d4); Albendazole (methyl-d3, propyl-1,1,2,2-d4); NSC 758724-d7; SKF 62979-d7; Zentel-d7
EINECS	Contact for details

Quality Control

Our Albendazole-D7 is manufactured under strict quality control protocols to ensure high chemical purity and isotopic enrichment suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity (atom % D), chemical purity (by HPLC), and identity confirmation (by NMR and MS). We adhere to relevant industry standards to support research under GLP and GMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity	≥98.0 atom % D
Chemical Purity	≥95.0% (by NMR)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.