Description

D-Serine, 3-Ethoxy-o-Ethyl-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]- is a sophisticated, high-purity protected amino acid derivative designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring precise molecular building blocks for complex organic synthesis, particularly in pharmaceutical development. It serves as a key intermediate for the synthesis of peptides, peptidomimetics, and other bioactive molecules, making it essential for the pharmaceutical, biotechnology, and advanced chemical research sectors.

Application

This specialized Fmoc-protected serine derivative is engineered for high-value applications in synthetic chemistry and life sciences.

• Pharmaceutical Intermediate: A crucial building block in the solid-phase and solution-phase synthesis of novel peptide-based therapeutics and drug candidates.
• Peptide Synthesis: Used for the controlled incorporation of modified serine residues into custom peptides and peptidomimetics.
• Bioconjugation: Serves as a linker or functional handle for attaching peptides to other molecules, surfaces, or biomolecules in drug delivery systems and diagnostic probes.
• Chemical Biology Research: Enables the study of protein structure-function relationships and enzyme mechanisms through the synthesis of site-specifically modified peptides.
• Process Development: Employed in the research and scale-up of manufacturing processes for complex active pharmaceutical ingredients (APIs).
• Academic & Industrial R&D: A vital reagent for synthetic organic chemistry laboratories focused on developing new methodologies and bioactive compounds.

Basic Information

Product Name	D-Serine, 3-Ethoxy-o-Ethyl-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-
CAS No.	1286768-52-2
Molecular Formula	C23H27NO6
Molecular Weight	413.47 g/mol
Synonyms	Fmoc-D-Ser(OEt)-OH; Fmoc-D-Ser(OEt) acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-ethoxy-D-serine; N-Fmoc-3-ethoxy-D-serine; D-Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 3-ethyl ether; Fmoc-D-Ser(OEt); (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-ethoxypropanoic acid
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and chiral integrity, NMR for structural confirmation, and mass spectrometry. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development under GMP-like conditions for pharmaceutical applications, with documentation available to meet rigorous audit requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.