Description

2-(Trifluoromethyl)Thiazole-5-Carboxylic Acid is a high-value heterocyclic building block characterized by its trifluoromethyl-substituted thiazole core. This compound matters for its role as a critical intermediate in the synthesis of advanced molecules, where the thiazole ring and fluorine atoms impart desirable biological and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antiviral, antibacterial, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized ligands or monomers in the development of specialty polymers and advanced materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-(Trifluoromethyl)Thiazole-5-Carboxylic Acid
CAS No.	1286734-84-6
Molecular Formula	C5H2F3NO2S
Molecular Weight	197.14 g/mol
Synonyms	5-Thiazolecarboxylic acid, 2-(trifluoromethyl)-; 2-(Trifluoromethyl)-1,3-thiazole-5-carboxylic acid; 2-Trifluoromethylthiazole-5-carboxylic acid; 2-(Trifluoromethyl)thiazole-5-carboxylic acid; 1286734-84-6; 2-Trifluoromethyl-5-thiazolecarboxylic acid; 2-(Trifluoromethyl)-5-thiazolecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Thiazole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.