Description

Aloe-Emodin-D5 is a high-purity, stable isotope-labeled internal standard of the natural anthraquinone derivative, aloe-emodin. This compound is essential for ensuring the accuracy and reliability of quantitative analytical methods, particularly in complex biological matrices. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, nutraceutical, and forensic toxicology sectors who require precise measurement of aloe-emodin and related compounds.

Application

• Quantitative Analytical Internal Standard: Primary use as a reference standard in Liquid Chromatography-Mass Spectrometry (LC-MS/MS) and High-Performance Liquid Chromatography (HPLC) for the accurate quantification of aloe-emodin.
• Pharmacokinetic and Metabolic Studies: Enables precise tracking of absorption, distribution, metabolism, and excretion (ADME) of aloe-emodin in preclinical and clinical research.
• Pharmaceutical Quality Control: Used in the assay and impurity profiling of drug substances and herbal medicinal products containing aloe-emodin or Aloe vera extracts.
• Forensic and Doping Analysis: Supports the identification and quantification of aloe-emodin in forensic toxicology and anti-doping control samples.
• Nutraceutical and Dietary Supplement Testing: Ensures label claim verification and safety assessment in products derived from aloe, rhubarb, senna, and cascara.
• Biomarker Research: Facilitates the development and validation of methods to measure aloe-emodin as a potential biomarker of exposure or efficacy.

Basic Information

Product Name	Aloe-Emodin-D5
CAS No.	1286579-72-3
Molecular Formula	C15H5D5O5
Molecular Weight	275.27 g/mol
Synonyms	1,8-Dihydroxy-3-(hydroxymethyl)-9,10-anthraquinone-d5; 1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone-d5; Aloe Emodin D5; Aloe-emodin (phenyl-D5); [D5]-Aloe-emodin; 3-Hydroxymethylchrysazin-d5; Rhein-9-anthrone-d5 (related metabolite); Isotopically Labeled Aloe-emodin
EINECS	Contact for details

Quality Control

Every batch of Aloe-Emodin-D5 is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure exceptional isotopic purity and chemical identity. Our quality commitment includes compliance with relevant standards for high-purity reference materials. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity (by HPLC), and spectroscopic confirmation is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, storage at -20°C is recommended.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (Mass Spectrometry)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D5)	≥ 98.0 atom % D
Chemical Purity (by HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.